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There are many approaches for treating psoriasis.
Put a mouse or a rat under stress and what does it do?
Coal tar--Preparations containing coal tar (gels and ointments) may be applied directly to the skin, added (as a liquid) to the bath, or used on the scalp as a shampoo.
TNF inhibitors are not FDA- approved for psoriasis, however, they are approved for other indications and physicians can prescribe them for psoriasis.
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Light therapy (phototherapy) is one type of treatment that can be used.
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Furthermore, the biomarker data from the plaque test correlate with biopsy data from the grafted mice.
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Topical corticosteroids have been the cornerstone of psoriasis therapy for many years.
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Comparative immunohistochemistry study was performed on the paraffin-sectioned psoriatic and healthy skins with the abovementioned markers.
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Castela E, Archier E, Devaux S, Gallini A, Aractingi S, Cribier B et al (2012) Topical corticosteroids in plaque psoriasis: a systematic review of risk of adrenal axis suppression and skin atrophy.
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Calcipotriol mono-treatment slightly enhanced the expression of MMP-1 and resulted in comparable levels of MMP-3 as found in the vehicle control.
This improvement continued with approximately 50% of patients showing at least marked improvement in the signs and symptoms of psoriasis after 8 weeks of therapy, but only approximately 4% showed complete clearing.
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